Regulation of Muscle Satellite Cell Activation and Cycles Consequent to Various Forms of Training

Authored by: Sophie Joanisse , Gianni Parise

The Routledge Handbook on Biochemistry of Exercise

Print publication date:  December  2020
Online publication date:  December  2020

Print ISBN: 9780367223830
eBook ISBN: 9781003123835
Adobe ISBN:


 Download Chapter



Skeletal muscle is a highly adaptable tissue and has the ability to repair and remodel when exposed to appropriate cues. Many factors act together allowing skeletal muscle to respond to a wide variety of stimuli such as physical activity, more specifically different modes of exercise training. Satellite cells, a skeletal muscle–specific stem cell population, are thought to play an important role in mediating adaptations due to exercise training. Increased satellite cell content has long been associated with hypertrophic stimuli in humans, such as resistance exercise training. Satellite cells are believed to contribute to the ability of muscle fibres to increase in size in response to resistance exercise training. In more recent years, researchers have sought to understand whether aerobic exercise also elicits a satellite cell response. In this chapter we discuss the ability of various forms of exercise to elicit acute and training responses of the satellite cell pool and the potential of these responses to mediate exercise-induced adaptations.

Search for more...
Back to top

Use of cookies on this website

We are using cookies to provide statistics that help us give you the best experience of our site. You can find out more in our Privacy Policy. By continuing to use the site you are agreeing to our use of cookies.