Advancements in Membrane Processes for Pharmaceutical Applications

Authored by: Ralf Kuriyel , Masatake Fushijima , Gary W. Jung

Handbook of Membrane Separations

Print publication date:  April  2015
Online publication date:  April  2015

Print ISBN: 9781466555563
eBook ISBN: 9781466555587
Adobe ISBN:

10.1201/b18319-16

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Abstract

Filtration- and membrane-based separation operations are used in the manufacture of many pharmaceutical products. These operations range, for example, from the clarification of fermentation broths used in the production of antibiotics to virus clearance for plasma-derived protein therapeutics, to sterile filtration of heat-labile products, and beyond. Innovations in membrane materials and module design allow membranes to be used in an increasingly wider range of manufacturing steps. This chapter describes different membrane technologies and their applications during the manufacture of pharmaceutical products such as antibiotics, plasma-derived proteins, active pharmaceutical ingredients, and parenterals (small and large volumes).

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