Lipid-Based Pulmonary Delivery System: A Review and Future Considerations of Formulation Strategies and Limitations

Authored by: Komal Parmar , Jayvadan Patel

Handbook of Lung Targeted Drug Delivery Systems

Print publication date:  October  2021
Online publication date:  October  2021

Print ISBN: 9780367490676
eBook ISBN: 9781003046547
Adobe ISBN:


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Active ingredients have been inhaled for millennia for various pharmacological actions. Nano-particulate systems provide efficient transport through the pulmonary route and thus have been extensively proposed for the lung drug delivery applications. Inhalation of lipid-based carrier demonstrates great potential for lung drug delivery which on successful entry in the pulmonary route allows the drug release in a controlled manner, further providing enhanced drug retention and minimized drug toxicity with local targeting. The present chapter addresses formulation considerations for lipid based nano-particulate drug delivery for the pulmonary route.

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