In Vivo Animal Models for Lung Targeted Drug Delivery Systems

Authored by: Khushali Vashi , Jasmin Patel , Yashwant Pathak

Handbook of Lung Targeted Drug Delivery Systems

Print publication date:  October  2021
Online publication date:  October  2021

Print ISBN: 9780367490676
eBook ISBN: 9781003046547
Adobe ISBN:


 Download Chapter



There have been several limitations associated with the conventional treatment choices available for targeted lung drug delivery systems. It is essential for both local and systemic treatment in the present-day pulmonary research to develop efficient, targeted drug delivery systems. Newer methods like aerosol absorption and nanoparticles have gained popularity in the modern scientific communities. The newer research models include use of computational fluid dynamics (CFD) and physiologically based pharmacokinetic (PBPK) models that are used to compute and mathematically analyze the drug delivery to the pulmonary system, making it more patient compliant and less toxic. This chapter focuses on the newer methods of pulmonary drug delivery using an extensive search of literature on the topic. This chapter aims to discuss the technical, physiological, and efficacy aspects of the newer pulmonary drug delivery systems that utilize the mathematical modeling. The chapter also aims to describe the mechanisms of administration of pulmonary medications along with compatibility of the drug, dosage, and devices used. Hence, this chapter provides better understanding of complex issues and challenges that are faced in the development of pulmonary drug delivery systems and offers an opportunity to the pharmaceutical scientist to understand the newer models and stimulations in the lung drug delivery systems and to aid in minimizing the clinical and technical gaps.

Search for more...
Back to top

Use of cookies on this website

We are using cookies to provide statistics that help us give you the best experience of our site. You can find out more in our Privacy Policy. By continuing to use the site you are agreeing to our use of cookies.