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Handbook of Lung Targeted Drug Delivery Systems

Recent Trends and Clinical Evidences

Edited by: Yashwant Pathak , Nazrul Islam

Print publication date:  October  2021
Online publication date:  October  2021

Print ISBN: 9780367490676
eBook ISBN: 9781003046547
Adobe ISBN:

10.1201/9781003046547
 Cite  Marc Record

Book description

Handbook of Lung Targeted Drug Delivery Systems: Recent Trends and Clinical Evidences covers every aspect of the drug delivery to lungs, the physiology and pharmacology of the lung, modelling for lung delivery, drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications. With the advent of nano sciences and significant development in the nano particulate drug delivery systems there has been a renewed interest in the lung as an absorption surface for various drugs. The emergence of the COVID-19 virus has brought lung and lung delivery systems into focus, this book covers new developments and research used to address the prevention and treatment of respiratory diseases. Written by well-known scientists with years of experience in the field this timely handbook is an excellent reference book for the scientists and industry professionals.

Key Features:

  • Focuses particularly on the chemistry, clinical pharmacology, and biological developments in this field of research.
  • Presents comprehensive information on emerging nanotechnology applications in diagnosing and treating pulmonary diseases
  • Explores drug devices focused on lung treatment, regulatory requirements, and recent trends in clinical applications
  • Examines specific formulations targeted to pulmonary systems

Table of contents

Prelims Download PDF
Chapter  1:  Introduction to Lung Physiology from a Drug Delivery Perspective Download PDF
Chapter  2:  Introduction to Pharmacology of the Lung from a Drug Delivery Perspective Download PDF
Chapter  3:  Mechanism and Ways of Pulmonary Drug Administration Download PDF
Chapter  4:  Transepithelial Route of Drug Delivery through the Pulmonary System Download PDF
Chapter  5:  Understanding the Pharmacokinetics and Pharmacodynamics of Lung and Lung Drug Delivery Download PDF
Chapter  6:  Chronic Lung Diseases: Treatment, Challenges, and Solutions Download PDF
Chapter  7:  Understanding of Lung Diseases with a Focus on Applications of Nano-particulate Drug Delivery Systems Download PDF
Chapter  8:  Model for Pharmaceutical aerosol transport through stenosis airway Download PDF
Chapter  9:  Design of Efficient Dry Powder Inhalers Download PDF
Chapter  10:  In Vivo Animal Models for Lung Targeted Drug Delivery Systems Download PDF
Chapter  11:  Advances in In Silico Study of Generic Orally Inhaled Drug Products Download PDF
Chapter  12:  Effect of Aerosol Devices and Administration Techniques on Drug Delivery in a Simulated Spontaneously Breathing Pediatric Tracheostomy Model Download PDF
Chapter  13:  Pulmonary Drug Delivery: The Role of Polymeric Nanoparticles Download PDF
Chapter  14:  Polymeric Nanoparticle-Based Drug–Gene Delivery for Lung Cancer Download PDF
Chapter  15:  Inhalable Polymeric Nano-particulate Powders for Respiratory Delivery Download PDF
Chapter  16:  Recent Trends in Applications of Nano-Drug Delivery Systems Download PDF
Chapter  17:  Nanocarrier Systems for Lung Drug Delivery Download PDF
Chapter  18:  Nanomedicine for the Management of Pulmonary Disorders Download PDF
Chapter  19:  Recent Approaches in Dendrimer-Based Pulmonary Drug Delivery Download PDF
Chapter  20:  Hybrid Lipid/Polymer Nanoparticles for Pulmonary Delivery of siRNA: Development and Fate Upon In Vitro Deposition on the Human Epithelial Airway Barrier Download PDF
Chapter  21:  Solid Lipid Nanoparticle-Based Drug Delivery for Lung Cancer Download PDF
Chapter  22:  Lipid-Based Pulmonary Delivery System: A Review and Future Considerations of Formulation Strategies and Limitations Download PDF
Chapter  23:  Respirable Controlled Release Polymeric Colloidal Nanoparticles Download PDF
Chapter  24:  Lung Clearance Kinetics of Liposomes and Solid Lipid Nanoparticles Download PDF
Chapter  25:  Solid Lipid Nanoparticles for Sustained Pulmonary Delivery of Herbal Drugs for Lung Delivery: Preparation, Characterization, and In Vivo Evaluation Download PDF
Chapter  26:  Improved Solid Lipid Nano-formulations for Pulmonary Delivery of Paclitaxel for Lung Cancer Therapy Download PDF
Chapter  27:  Anti-angiogenic Therapy for Lung Cancer: Focus on Bioassay Development in a Quest for Anti-VEGF Drugs Download PDF
Chapter  28:  Emerging Applications of Nanoparticles for Lung Cancer Diagnosis and Therapy Download PDF
Chapter  29:  Metallic Nanoparticles: Technology Overview and Drug Delivery Applications in Lung Cancer Download PDF
Chapter  30:  Modeling of Pharmaceutical Aerosol Transport in the Targeted Region of Human Lung Airways Due to External Magnetic Field Download PDF
Chapter  31:  Phytochemicals and Biogenic Metallic Nanoparticles as Anti-cancer Agents in Lung Cancer Download PDF
Chapter  32:  Pulmonary Applications and Toxicity of Engineered Metallic Nanoparticles Download PDF
Chapter  33:  Anti-cancer Activity of Eco-friendly Gold Nanoparticles against Lung and Liver Cancer Cells Download PDF
Chapter  34:  Sub-chronic Inhalational Toxicity Studies for Gold Nanoparticles Download PDF
Chapter  35:  Single-Use Dry Powder Inhalers for Pulmonary Drug Delivery Download PDF
Chapter  36:  Lung Delivery of Nicotine for Smoking Cessation Download PDF
Chapter  37:  Formulation and Characterization of Dry Powder Inhalers for Pulmonary Drug Delivery Download PDF
Chapter  38:  Devices for Dry Powder Drug Delivery to the Lung Download PDF
Chapter  39:  Numerical Modeling of Agglomeration and De-agglomeration in Dry Powder Inhalers Download PDF
Chapter  40:  Oronasal and Tracheostomy Delivery of Soft Mist and Pressurized Metered-Dose Inhalers with Valved Holding Chamber Download PDF
Chapter  41:  Modeling for Biopharmaceutical Performance in Lung Drug Discovery Download PDF
Chapter  42:  Regulatory Consideration for Approval of Generic Inhalation Drug Products in the US, EU, Brazil, China, and India Download PDF
Chapter  43:  Regulatory Perspectives and Concerns Related to Nanoparticle-Based Lung Delivery Download PDF
Chapter  44:  Clinical Controversies of Pediatric Aerosol Therapy Download PDF
Chapter  45:  Drug Delivery Using Aerosols: Challenges and Advances in Neonatal Pediatric Subgroup Download PDF
Chapter  46:  Safety and Toxicological Concerns Related to Nanoparticle-Based Lung Delivery Download PDF
Chapter  47:  Nanoparticle-Based Lung Drug Delivery: A Clinical Perspective Download PDF
Chapter  48:  European Perspective on Orally Inhaled Products: In Vitro Requirements for a Biowaiver Download PDF
Index Download PDF
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